human MSMB shRNA silencing AAV

Name
AAV-h-MSMB-shRNA

Cat No
shAAV-215925

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MSMB.

shAAV-215925

AAV-h-MSMB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MSMB (microseminoprotein beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HPC13; IGBF; MSP; MSPB; PN44; PRPS; PSP; PSP-94; PSP57; PSP94

Description (Vector)

MSMB is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene.

Gene ID

4477

Gene Name (Vector)

microseminoprotein beta

Gene Symbol

MSMB

HGNC ID

HGNC:7372

ORF Size (aa)

345

RefSeq ID

NM_002443

RefSeq Synonyms

NM_138634, NM_002443, BC005257,

Species

human

UniGene ID

Hs.255462

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.