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human MRPS36 shRNA silencing AAV

Name 
AAV-h-MRPS36-shRNA
Cat No 
shAAV-215872
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MRPS36.

shAAV-215872
AAV-h-MRPS36-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MRPS36 (mitochondrial ribosomal protein S36). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
28S ribosomal protein S36, mitochondrial; DC47; MRP-S36; S36mt
Description (eCommerce)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. The gene MRPS36 encodes a 28S subunit protein, 28S ribosomal protein S36, mitochondrial [taken from NCBI Entrez Gene (Gene ID: 92259)].
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p.
Gene ID
92259
Gene Name (eCommerce)
mitochondrial ribosomal protein S36
Gene Name (Vector)
mitochondrial ribosomal protein S36
Gene Symbol
MRPS36
HGNC ID
HGNC:16631
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
312
Protein Name (eCommerce)
28S ribosomal protein S36, mitochondrial
RefSeq ID
NM_033281
RefSeq Synonyms
NM_033281, BC017900, BC015966,
Research Areas
Mitochondrion,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. The gene MRPS36 encodes a 28S subunit protein, 28S ribosomal protein S36, mitochondrial [taken from NCBI Entrez Gene (Gene ID: 92259)].
UniGene ID
Hs.631971
UniProt ID (eCommerce)
P82909

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.