human MRPS2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MRPS2.
shAAV-215856
AAV-h-MRPS2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MRPS2 (mitochondrial ribosomal protein S2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-91; MRP-S2; S2mt
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene.
Gene ID
51116
Gene Name (Vector)
mitochondrial ribosomal protein S2
Gene Symbol
MRPS2
HGNC ID
HGNC:14495
ORF Size (aa)
891
ORF Size (bp)
891 bp
RefSeq ID
NM_016034
RefSeq Synonyms
NM_016034, BC013108, BC008017,
Species
human
UniGene ID
Hs.382044
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.