human MPST shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MPST.
shAAV-215731
AAV-h-MPST-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MPST (mercaptopyruvate sulfurtransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MST; TST2; TUM1
Description (Vector)
This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene.
Gene ID
4357
Gene Name (Vector)
mercaptopyruvate sulfurtransferase
Gene Symbol
MPST
HGNC ID
HGNC:7223
ORF Size (aa)
894
RefSeq ID
NM_021126
RefSeq Synonyms
NM_021126, NM_001130517, NM_001013436, BC018717, BC016737, BC003508,
Species
human
UniGene ID
Hs.248267
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.