human MOV10 shRNA silencing AAV

Name
AAV-h-MOV10-shRNA

Cat No
shAAV-215690

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MOV10.

shAAV-215690

AAV-h-MOV10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MOV10 (Mov10 RISC complex RNA helicase). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

armitage homolog; fSAP113; functional spliceosome-associated protein 113; gb110; moloney leukemia virus 10 protein; Mov10, Moloney leukemia virus 10, homolog; putative helicase MOV-10

Description (eCommerce)

Moloney leukemia virus 10 protein (MOV10) is putative RNA helicase that has been identified as a factor associated with argonaute (Ago) containing complexes. Ago complexes play a central in micro RNA (miRNA) and short-interference RNA (siRNA) silencing.

Gene ID

4343

Gene Name (eCommerce)

Mov10 RISC complex RNA helicase

Gene Name (Vector)

Mov10 RISC complex RNA helicase

Gene Symbol

MOV10

HGNC ID

HGNC:7200

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3012

ORF Size (bp)

3012 bp

Protein Name (eCommerce)

Putative helicase MOV-10

RefSeq ID

NM_020963

RefSeq Synonyms

NM_020963, NM_001321324, NM_001286072, NM_001130079, BC009312, BC002548,

Research Areas

B-cell Receptor Signaling,Cancer,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,Helicase Activity,Immunology,Innate Immunity,Neurobiology,NGF Signaling,Notch Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,RNA Binding,RNA Processing,SCF-KIT Signaling,Signal Transduction,Transcription Factor/Regulator,Translational Control

Research Areas (Faceted)

cancer,cell_biology,developmental_biology,genetics,immunology,neurobiology,signal_transduction,stem_cell_biology,transcription_translation

Species

human

Target Sentence

UniGene ID

Hs.514941

UniProt ID (eCommerce)

Q9HCE1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.