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human MOCS1 shRNA silencing AAV

Name 
AAV-h-MOCS1-shRNA
Cat No 
shAAV-215629
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MOCS1.

shAAV-215629
AAV-h-MOCS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MOCS1 (molybdenum cofactor synthesis 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MIG11; MOCOD; MOCODA
Description (Vector)
Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants, whose full-length natures have yet to be determined, are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16.
Gene ID
4337
Gene Name (Vector)
molybdenum cofactor synthesis 1
Gene Symbol
MOCS1
HGNC ID
HGNC:7190
ORF Size (aa)
1908
ORF Size (bp)
1908 bp
RefSeq ID
NM_005943
RefSeq Synonyms
NM_005943, NM_001075098, BC140421,
Species
human
UniGene ID
Hs.718492

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.