human MNAT1 shRNA silencing AAV

Name
AAV-h-MNAT1-shRNA

Cat No
shAAV-215613

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MNAT1.

shAAV-215613

AAV-h-MNAT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MNAT1 (MNAT1, CDK activating kinase assembly factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CAP35; MAT1; RNF66; TFB3

Description (Vector)

MNAT1, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

4331

Gene Name (Vector)

MNAT1, CDK activating kinase assembly factor

Gene Symbol

MNAT1

HGNC ID

HGNC:7181

ORF Size (aa)

930

ORF Size (bp)

930 bp

RefSeq ID

NM_002431

RefSeq Synonyms

NM_002431, NM_001177963, BC000820,

Species

human

UniGene ID

Hs.509523

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.