human MMP21 shRNA silencing AAV

Name
AAV-h-MMP21-shRNA

Cat No
shAAV-215588

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MMP21.

shAAV-215588

AAV-h-MMP21-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MMP21 (matrix metallopeptidase 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HTX7; MMP-21

Description (Vector)

MMP21 encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling,and disease processes, such as asthma and metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival.

Gene ID

118856

Gene Name (Vector)

matrix metallopeptidase 21

Gene Symbol

MMP21

HGNC ID

HGNC:14357

ORF Size (aa)

1707

ORF Size (bp)

1707 bp

RefSeq ID

NM_147191

RefSeq Synonyms

NM_147191, BC172493, BC156368,

Species

human

UniGene ID

Hs.314141

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.