human MLYCD shRNA silencing AAV

Name
AAV-h-MLYCD-shRNA

Cat No
shAAV-215545

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MLYCD.

shAAV-215545

AAV-h-MLYCD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MLYCD (malonyl-CoA decarboxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MCD

Description (Vector)

The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.

Gene ID

23417

Gene Name (Vector)

malonyl-CoA decarboxylase

Gene Symbol

MLYCD

HGNC ID

HGNC:7150

ORF Size (aa)

1365

ORF Size (bp)

1365 bp

RefSeq ID

NM_012213

RefSeq Synonyms

NM_012213, BC052592, BC000286,

Species

human

UniGene ID

Hs.644610

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.