human MESP2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MESP2.
shAAV-215313
AAV-h-MESP2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MESP2 (mesoderm posterior bHLH transcription factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHc6; SCDO2
Description (Vector)
MESP2 encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. MESP2 is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. MESP2 also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).
Gene ID
145873
Gene Name (Vector)
mesoderm posterior bHLH transcription factor 2
Gene Symbol
MESP2
HGNC ID
HGNC:29659
ORF Size (aa)
1182
ORF Size (bp)
1182 bp
RefSeq ID
NM_001039958
RefSeq Synonyms
NM_001039958, BC111413,
Species
human
UniGene ID
Hs.37311
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.