human MDFI shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MDFI.
shAAV-215209
AAV-h-MDFI-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MDFI (MyoD family inhibitor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
I-MF; I-mfa
Description (Vector)
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Gene ID
4188
Gene Name (Vector)
MyoD family inhibitor
Gene Symbol
MDFI
HGNC ID
HGNC:6967
ORF Size (aa)
741
RefSeq ID
NM_005586
RefSeq Synonyms
NM_005586, NM_001300806, NM_001300805, NM_001300804, BC007836,
Species
human
UniGene ID
Hs.520119
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.