human MCPH1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MCPH1.
shAAV-215201
AAV-h-MCPH1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MCPH1 (microcephalin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BRIT1; MCT
Description (Vector)
MCPH1 encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.
Gene ID
79648
Gene Name (Vector)
microcephalin 1
Gene Symbol
MCPH1
HGNC ID
HGNC:6954
ORF Size (aa)
1833
ORF Size (bp)
1833 bp
RefSeq ID
NM_024596
RefSeq Synonyms
NM_024596, NM_001322045, NM_001322043, NM_001322042, NM_001172575, NM_001172574, BC030702,
Species
human
UniGene ID
Hs.709634
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.