human MARS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MARS.
shAAV-215040
AAV-h-MARS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MARS (methionyl-tRNA synthetase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMT2U; cytosolic methionyl-tRNA synthetase; ILFS2; ILLD; methionine--tRNA ligase, cytoplasmic; Methionyl-tRNA synthetase; METRS; MRS; MTRNS; SPG70
Description (eCommerce)
Methionyl-tRNA synthetase (MARS) is a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [taken from NCBI Entrez Gene (Gene ID: 4141)].
Description (Vector)
MARS encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules.
Gene ID
4141
Gene Name (eCommerce)
methionyl-tRNA synthetase
Gene Name (Vector)
methionyl-tRNA synthetase
Gene Symbol
MARS
HGNC ID
HGNC:6898
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2703
ORF Size (bp)
2703 bp
Protein Name (eCommerce)
Methionine--tRNA ligase, cytoplasmic
RefSeq ID
NM_004990
RefSeq Synonyms
NM_004990, BC011849, BC011639, BC006328, BC002384,
Research Areas
Gene Expression,Metabolism/Metabolic Process,Mitochondrion,RNA Binding,RNA Processing,Translational Control,tRNA Binding
Research Areas (Faceted)
genetics,transcription_translation,metabolism,cell_biology
Species
human
Target Sentence
Methionyl-tRNA synthetase (MARS) is a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [taken from NCBI Entrez Gene (Gene ID: 4141)].
UniGene ID
Hs.632707
UniProt ID (eCommerce)
P56192
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.