human MANBA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MANBA.
shAAV-214885
AAV-h-MANBA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MANBA (mannosidase beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MANB1
Description (Vector)
MANBA encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement.
Gene ID
4126
Gene Name (Vector)
mannosidase beta
Gene Symbol
MANBA
HGNC ID
HGNC:6831
ORF Size (aa)
2640
ORF Size (bp)
2640 bp
RefSeq ID
NM_005908
RefSeq Synonyms
NM_005908, BC015743,
Species
human
UniGene ID
Hs.480415
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.