human MAGEB2 shRNA silencing AAV

Name
AAV-h-MAGEB2-shRNA

Cat No
shAAV-214826

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MAGEB2.

shAAV-214826

AAV-h-MAGEB2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAGEB2 (MAGE family member B2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CT3.2; DAM6; MAGE-XP-2

Description (Vector)

MAGEB2 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. MAGEB2 is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.

Gene ID

4113

Gene Name (Vector)

MAGE family member B2

Gene Symbol

MAGEB2

HGNC ID

HGNC:6809

ORF Size (aa)

960

ORF Size (bp)

960 bp

RefSeq ID

NM_002364

RefSeq Synonyms

NM_002364, BC026071,

Species

human

UniGene ID

Hs.113824

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.