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human MAGEB1 shRNA silencing AAV

Name 
AAV-h-MAGEB1-shRNA
Cat No 
shAAV-214820
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAGEB1.

shAAV-214820
AAV-h-MAGEB1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAGEB1 (MAGE family member B1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CT3.1; DAM10; MAGE-Xp; MAGEL1
Description (Vector)
MAGEB1 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. MAGEB1 is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. MAGEB1 and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined.
Gene ID
4112
Gene Name (Vector)
MAGE family member B1
Gene Symbol
MAGEB1
HGNC ID
HGNC:6808
ORF Size (aa)
1044
ORF Size (bp)
1044 bp
RefSeq ID
NM_002363
RefSeq Synonyms
NM_177415, NM_177404, NM_002363, BC013772,
Species
human
UniGene ID
Hs.73021

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.