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human MAGEA4 shRNA silencing AAV

Name 
AAV-h-MAGEA4-shRNA
Cat No 
shAAV-214811
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAGEA4.

shAAV-214811
AAV-h-MAGEA4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAGEA4 (MAGE family member A4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CT1.4; MAGE-41; MAGE-X2; MAGE4; MAGE4A; MAGE4B
Description (Vector)
MAGEA4 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.
Gene ID
4103
Gene Name (Vector)
MAGE family member A4
Gene Symbol
MAGEA4
HGNC ID
HGNC:6802
ORF Size (aa)
954
ORF Size (bp)
954 bp
RefSeq ID
NM_002362
RefSeq Synonyms
NM_002362, NM_001011550, NM_001011549, NM_001011548, BC017723,
Species
human
UniGene ID
Hs.37107

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.