human LTF shRNA silencing AAV

Name 
AAV-h-LTF-shRNA
Cat No 
shAAV-214669
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LTF.

shAAV-214669
AAV-h-LTF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LTF (lactotransferrin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis luminal protein 110; GIG12; growth-inhibiting protein 12; HEL110; HLF2; kaliocin-1; lactoferricin; Lactoferrin; lactoferroxin; lactotransferrin; LF; neutrophil lactoferrin; talalactoferrin
Description (eCommerce)
Lactoferrin is a milk protein whose presence is greater in colostrum. Contributes to both iron transport and has antibacterial properties as well.
Description (Vector)
LTF is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
4057
Gene Name (eCommerce)
lactotransferrin
Gene Name (Vector)
lactotransferrin
Gene Symbol
LTF
HGNC ID
HGNC:6720
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2136
ORF Size (bp)
2136 bp
Protein Name (eCommerce)
Lactotransferrin
RefSeq ID
NM_002343
RefSeq Synonyms
NM_002343, NM_001321122, NM_001321121, NM_001199149, BC022347, BC015823, BC015822,
Research Areas
Immunology,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
Lactoferrin is a milk protein whose presence is greater in colostrum. Contributes to both iron transport and has antibacterial properties as well.
UniGene ID
Hs.529517
UniProt ID (eCommerce)
P02788

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.