human NEK6 shRNA silencing AAV

Name 
AAV-h-NEK6-shRNA
Cat No 
shAAV-214314
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NEK6.

shAAV-214314
AAV-h-NEK6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NEK6 (NIMA related kinase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SID6-1512
Description (Vector)
NEK6 is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene ID
10783
Gene Name (Vector)
NIMA related kinase 6
Gene Symbol
NEK6
HGNC ID
HGNC:7749
ORF Size (aa)
942
ORF Size (bp)
942 bp
RefSeq ID
NM_014397
RefSeq Synonyms
NM_014397, NM_001166171, NM_001166170, NM_001166169, NM_001166168, NM_001166167, NM_001145001, BC012761, BC004209, BC004174, BC000101,
Species
human
UniGene ID
Hs.197071

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.