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human GAS2 shRNA silencing AAV

Name 
AAV-h-GAS2-shRNA
Cat No 
shAAV-214187
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GAS2.

shAAV-214187
AAV-h-GAS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GAS2 (growth arrest specific 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
87
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
GAS2 is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
2620
Gene Name (Vector)
growth arrest specific 2
Gene Symbol
GAS2
HGNC ID
HGNC:4167
ORF Size (aa)
942
ORF Size (bp)
942 bp
RefSeq ID
NM_005256
RefSeq Synonyms
NM_177553, NM_005256, NM_001143830, BC040470, BC013326,
Species
human
UniGene ID
Hs.632151

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.