human ZIC1 shRNA silencing AAV

Name
AAV-h-ZIC1-shRNA

Cat No
shAAV-214173

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ZIC1.

shAAV-214173

AAV-h-ZIC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZIC1 (Zic family member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CRS6; ZIC; ZNF201

Description (Vector)

ZIC1 encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. ZIC1 is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. ZIC1 encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.

Gene ID

7545

Gene Name (Vector)

Zic family member 1

Gene Symbol

ZIC1

HGNC ID

HGNC:12872

ORF Size (aa)

1344

RefSeq ID

NM_003412

RefSeq Synonyms

NM_003412, BC104850, BC104848,

Species

human

UniGene ID

Hs.598590

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.