human PSCA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PSCA.
shAAV-214165
AAV-h-PSCA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PSCA (prostate stem cell antigen). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PRO232
Description (Vector)
PSCA encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. PSCA is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. PSCA includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
Gene ID
8000
Gene Name (Vector)
prostate stem cell antigen
Gene Symbol
PSCA
HGNC ID
HGNC:9500
ORF Size (aa)
372
RefSeq ID
NM_005672
RefSeq Synonyms
NM_005672, BC065183, BC023582,
Species
human
UniGene ID
Hs.711174
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.