human JPH4 shRNA silencing AAV

Name
AAV-h-JPH4-shRNA

Cat No
shAAV-214139

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human JPH4.

shAAV-214139

AAV-h-JPH4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human JPH4 (junctophilin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

JP4; JPHL1

Description (Vector)

JPH4 encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants.

Gene ID

84502

Gene Name (Vector)

junctophilin 4

Gene Symbol

JPH4

ORF Size (aa)

1887

ORF Size (bp)

1887 bp

RefSeq ID

NM_032452

RefSeq Synonyms

NM_032452, NM_001146028, BC055429,

Species

human

UniGene ID

Hs.597841

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.