human SPTB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SPTB.
shAAV-214099
AAV-h-SPTB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SPTB (spectrin beta, erythrocytic). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EL3; HS2; HSPTB1; SPH2
Description (Vector)
This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described.
Gene ID
6710
Gene Name (Vector)
spectrin beta, erythrocytic
Gene Symbol
SPTB
HGNC ID
HGNC:11274
ORF Size (aa)
6414
ORF Size (bp)
6414 bp
RefSeq ID
NM_000347
RefSeq Synonyms
NM_001024858, NM_000347, BC136285, BC136284, BC010434,
Species
human
UniGene ID
Hs.417303
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.