human MGAT1 shRNA silencing AAV

Name
AAV-h-MGAT1-shRNA

Cat No
shAAV-214065

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MGAT1.

shAAV-214065

AAV-h-MGAT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MGAT1 (mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; GnTI; MGAT

Description (Vector)

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.

Gene ID

4245

Gene Name (Vector)

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

Gene Symbol

MGAT1

HGNC ID

HGNC:7044

ORF Size (aa)

1338

ORF Size (bp)

1338 bp

RefSeq ID

NM_002406

RefSeq Synonyms

NM_002406, NM_001114620, NM_001114619, NM_001114618, NM_001114617, BC003575,

Species

human

UniGene ID

Hs.519818

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.