human LMNB2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LMNB2.
shAAV-214030
AAV-h-LMNB2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LMNB2 (lamin B2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EPM9; LAMB2; LMN2
Description (Vector)
LMNB2 encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.
Gene ID
84823
Gene Name (Vector)
lamin B2
Gene Symbol
LMNB2
HGNC ID
HGNC:6638
ORF Size (aa)
1803
ORF Size (bp)
1803 bp
RefSeq ID
NM_032737
RefSeq Synonyms
NM_032737, BC006551,
Species
human
UniGene ID
Hs.538286
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.