human LMBR1 shRNA silencing AAV

Name
AAV-h-LMBR1-shRNA

Cat No
shAAV-214011

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human LMBR1.

shAAV-214011

AAV-h-LMBR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LMBR1 (limb development membrane protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACHP; C7orf2; DIF14; LSS; PPD2; THYP; TPT; ZRS

Description (Vector)

LMBR1 encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.

Gene ID

64327

Gene Name (Vector)

limb development membrane protein 1

Gene Symbol

LMBR1

HGNC ID

HGNC:13243

ORF Size (aa)

1473

ORF Size (bp)

1473 bp

RefSeq ID

NM_022458

RefSeq Synonyms

NM_022458, BC017663,

Species

human

UniGene ID

Hs.209989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.