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human LLGL2 shRNA silencing AAV

Name 
AAV-h-LLGL2-shRNA
Cat No 
shAAV-214002
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LLGL2.

shAAV-214002
AAV-h-LLGL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LLGL2 (LLGL2, scribble cell polarity complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HGL; Hugl-2; LGL2
Description (Vector)
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
3993
Gene Name (Vector)
LLGL2, scribble cell polarity complex component
Gene Symbol
LLGL2
ORF Size (aa)
3063
ORF Size (bp)
3063 bp
RefSeq ID
NM_004524
RefSeq Synonyms
NM_004524, NM_001031803, NM_001015002, BC064994,
Species
human
UniGene ID
Hs.514477

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.