human LGTN shRNA silencing AAV

Name 
AAV-h-LGTN-shRNA
Cat No 
shAAV-213883
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EIF2D.

shAAV-213883
AAV-h-LGTN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EIF2D (eukaryotic translation initiation factor 2D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
eIF2d; eukaryotic translation initiation factor 2D; HCA56; hepatocellular carcinoma-associated antigen 56; LGTN; ligatin
Description (eCommerce)
Ligatin is also known as EIF2D (eukaryotic translation initiation factor 2D). Ligatin functions as a trafficking receptor for phosphoglycoproteins. Recently, ligatin has been shown to also function as a translation initiation factor.
Description (Vector)
EIF2D encodes a translation initiation factor involved in the recruitment and delivery of aminoacyl-tRNAs to the P-site of the eukaryotic ribosome in a GTP-independent manner. EIF2D was previously referred to as ligatin, but is now known to localize to the cytoplasm and localize and function with translation factors. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
1939
Gene Name (eCommerce)
eukaryotic translation initiation factor 2D
Gene Name (Vector)
eukaryotic translation initiation factor 2D
Gene Symbol
EIF2D
HGNC ID
HGNC:6583
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1755
ORF Size (bp)
1755 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 2D
RefSeq ID
NM_006893
RefSeq Synonyms
NM_006893, NM_001201478, BC058905, BC039134, BC001585,
Research Areas
Translational Control,Transport
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Ligatin is also known as EIF2D (eukaryotic translation initiation factor 2D). Ligatin functions as a trafficking receptor for phosphoglycoproteins. Recently, ligatin has been shown to also function as a translation initiation factor.
UniGene ID
Hs.497581
UniProt ID (eCommerce)
P41214

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.