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human LGSN shRNA silencing AAV

Name 
AAV-h-LGSN-shRNA
Cat No 
shAAV-213881
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LGSN.

shAAV-213881
AAV-h-LGSN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LGSN (lengsin, lens protein with glutamine synthetase domain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GLULD1; LGS
Description (Vector)
LGSN encodes a protein with similarity to the GS I members of the glutamine synthetase superfamily. The encoded protein is referred to as a pseudo-glutamine synthetase because it has no glutamine synthesis activity and may function as a chaperone protein. This protein is localized to the lens and may be associated with cataract disease. Alternative splicing results in multiple transcript variants.
Gene ID
51557
Gene Name (Vector)
lengsin, lens protein with glutamine synthetase domain
Gene Symbol
LGSN
HGNC ID
HGNC:21016
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
RefSeq ID
NM_016571
RefSeq Synonyms
NM_016571, NM_001143940, BC130368, BC130366,
Species
human
UniGene ID
Hs.149585

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.