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human LEPREL2 shRNA silencing AAV

Name 
AAV-h-LEPREL2-shRNA
Cat No 
shAAV-213838
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human P3H3.

shAAV-213838
AAV-h-LEPREL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human P3H3 (prolyl 3-hydroxylase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GRCB; HSU47926; LEPREL2
Description (Vector)
LEPREL2 belongs to a family of collagen prolyl hydroxylases required for proper collagen biosynthesis, folding, and assembly (Vranka et al., 2004 (PubMed 15044469)).(supplied by OMIM, Mar 2008)
Gene ID
10536
Gene Name (Vector)
prolyl 3-hydroxylase 3
Gene Symbol
P3H3
HGNC ID
HGNC:19318
ORF Size (aa)
2211
ORF Size (bp)
2211 bp
RefSeq ID
NM_014262
RefSeq Synonyms
NM_014262, BC157128, BC156266, BC017217,
Species
human
UniGene ID
Hs.631655

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.