human LDHB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LDHB.
shAAV-213788
AAV-h-LDHB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LDHB (lactate dehydrogenase B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
epididymis secretory protein Li 281; HEL-S-281; lactate dehydrogenase H chain; LDH heart subunit; LDH-B; LDHBD; LDH-H; L-lactate dehydrogenase B chain; renal carcinoma antigen NY-REN-46; testicular secretory protein Li 25; TRG-5
Description (eCommerce)
Lactate Dehydrogenase B / LDHB is an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency [taken from NCBI Entrez Gene (Gene ID: 3945)].
Description (Vector)
LDHB encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
3945
Gene Name (eCommerce)
lactate dehydrogenase B
Gene Name (Vector)
lactate dehydrogenase B
Gene Symbol
LDHB
HGNC ID
HGNC:6541
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1005
ORF Size (bp)
1005 bp
Protein Name (eCommerce)
L-lactate dehydrogenase B chain
RefSeq ID
NM_002300
RefSeq Synonyms
NM_002300, NM_001315537, NM_001174097, BC071860, BC015122, BC002362,
Research Areas
Immunology,Metabolism/Metabolic Process,Mitochondrion,T-cell Receptor Signaling
Research Areas (Faceted)
cell_biology,immunology,metabolism,signal_transduction
Species
human
Target Sentence
Lactate Dehydrogenase B / LDHB is an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency [taken from NCBI Entrez Gene (Gene ID: 3945)].
UniGene ID
Hs.446149
UniProt ID (eCommerce)
P07195
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.