human LAP3 shRNA silencing AAV

Name 
AAV-h-LAP3-shRNA
Cat No 
shAAV-213666
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LAP3.

shAAV-213666
AAV-h-LAP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LAP3 (leucine aminopeptidase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cytosol aminopeptidase; epididymis secretory protein Li 106; HEL-S-106; LAP; LAP-3; LAPEP; Leucine aminopeptidase 3; leucyl aminopeptidase; PEPS; peptidase S; proline aminopeptidase; prolyl aminopeptidase
Description (eCommerce)
LAP3 is a cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme.  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P28838].
Gene ID
51056
Gene Name (eCommerce)
leucine aminopeptidase 3
Gene Name (Vector)
leucine aminopeptidase 3
Gene Symbol
LAP3
HGNC ID
HGNC:18449
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1560
ORF Size (bp)
1560 bp
Protein Name (eCommerce)
Cytosol aminopeptidase
RefSeq ID
NM_015907
RefSeq Synonyms
NM_015907, BC065564,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
LAP3 is a cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme.  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P28838].
UniGene ID
Hs.570791
UniProt ID (eCommerce)
P28838

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.