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human LANCL1 shRNA silencing AAV

Name 
AAV-h-LANCL1-shRNA
Cat No 
shAAV-213662
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LANCL1.

shAAV-213662
AAV-h-LANCL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LANCL1 (LanC like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
40 kDa erythrocyte membrane protein; G protein-coupled receptor 69A; GPR69A; LanC (bacterial lantibiotic synthetase component C)-like 1; LanC (bacterial lantibiotic synthetase component); LanC lantibiotic synthetase component C-like 1; lanC-like protein 1; p40
Description (eCommerce)
LanC lantibiotic synthetase component C-like 1 (LANCL1) is a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. LANCL1 was previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family [taken from NCBI Entrez Gene (Gene ID: 10314)].
Description (Vector)
LANCL1 encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
10314
Gene Name (eCommerce)
LanC like 1
Gene Name (Vector)
LanC like 1
Gene Symbol
LANCL1
HGNC ID
HGNC:6508
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1200
ORF Size (bp)
1200 bp
Protein Name (eCommerce)
LanC-like protein 1
RefSeq ID
NM_006055
RefSeq Synonyms
NM_006055, NM_001136575, NM_001136574, BC028685,
Research Areas
Cytoskeleton,Metabolism/Metabolic Process,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,metabolism
Species
human
Target Sentence
LanC lantibiotic synthetase component C-like 1 (LANCL1) is a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. LANCL1 was previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family [taken from NCBI Entrez Gene (Gene ID: 10314)].
UniGene ID
Hs.13351
UniProt ID (eCommerce)
O43813

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.