human L2HGDH shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human L2HGDH.
shAAV-213624
AAV-h-L2HGDH-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human L2HGDH (L-2-hydroxyglutarate dehydrogenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C14orf160; L2HGA
Description (Vector)
L2HGDH encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.
Gene ID
79944
Gene Name (Vector)
L-2-hydroxyglutarate dehydrogenase
Gene Symbol
L2HGDH
HGNC ID
HGNC:20499
ORF Size (aa)
1326
ORF Size (bp)
1326 bp
RefSeq ID
NM_024884
RefSeq Synonyms
NM_024884, BC006117,
Species
human
UniGene ID
Hs.256034
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.