human KRT10 shRNA silencing AAV

Name 
AAV-h-KRT10-shRNA
Cat No 
shAAV-213374
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KRT10.

shAAV-213374
AAV-h-KRT10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KRT10 (keratin 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BCIE; BIE; CK-10; CK10; Cytokeratin-10; EHK; K10; KPP; Keratin-10; cytokeratin 10; keratin 10, type I; keratin, type I cytoskeletal 10
Description (Vector)
KRT10 encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. KRT10 is located within a cluster of keratin family members on chromosome 17q21.
Gene ID
3858
Gene Name (eCommerce)
keratin 10
Gene Name (Vector)
keratin 10
Gene Symbol
KRT10
HGNC ID
HGNC:6413
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1755
ORF Size (bp)
1755 bp
Protein Name (eCommerce)
Keratin, type I cytoskeletal 10
RefSeq ID
NM_000421
RefSeq Synonyms
NM_000421, BC034697,
Research Areas
Cell Biology,Immune Cells and Tumor Markers,Immuno-Oncology
Research Areas (Faceted)
cell_biology,immuno_oncology
Species
human
UniGene ID
Hs.99936
UniProt ID (eCommerce)
P13645

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.