human KRT1 shRNA silencing AAV

Name 
AAV-h-KRT1-shRNA
Cat No 
shAAV-213373
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KRT1.

shAAV-213373
AAV-h-KRT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KRT1 (keratin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CK1; EHK; EHK1; EPPK; K1; KRT1A; NEPPK
Description (Vector)
KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Gene ID
3848
Gene Name (Vector)
keratin 1
Gene Symbol
KRT1
HGNC ID
HGNC:6412
ORF Size (aa)
1935
ORF Size (bp)
1935 bp
RefSeq ID
NM_006121
RefSeq Synonyms
NM_006121, BC063697,
Species
human
UniGene ID
Hs.80828

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.