human KLK6 shRNA silencing AAV

Name 
AAV-h-KLK6-shRNA
Cat No 
shAAV-213302
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KLK6.

shAAV-213302
AAV-h-KLK6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KLK6 (kallikrein related peptidase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Bssp; hK6; Klk7; PRSS18; PRSS9; SP59
Description (Vector)
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Gene ID
5653
Gene Name (Vector)
kallikrein related peptidase 6
Gene Symbol
KLK6
HGNC ID
HGNC:6367
ORF Size (aa)
735
RefSeq ID
NM_002774
RefSeq Synonyms
NM_002774, NM_001319949, NM_001319948, NM_001012965, NM_001012964, BC015525,
Species
human
UniGene ID
Hs.79361

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.