human KLK2 shRNA silencing AAV

Name 
AAV-h-KLK2-shRNA
Cat No 
shAAV-213290
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KLK2.

shAAV-213290
AAV-h-KLK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KLK2 (kallikrein related peptidase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hGK-1; hK2; KLK2A2
Description (Vector)
KLK2 encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. KLK2 is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.
Gene ID
3817
Gene Name (Vector)
kallikrein related peptidase 2
Gene Symbol
KLK2
HGNC ID
HGNC:6363
ORF Size (aa)
786
ORF Size (bp)
786 bp
RefSeq ID
NM_005551
RefSeq Synonyms
NM_005551, NM_001256080, NM_001002231, BC005196,
Species
human
UniGene ID
Hs.515560

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.