human KLK15 shRNA silencing AAV

Name
AAV-h-KLK15-shRNA

Cat No
shAAV-213286

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KLK15.

shAAV-213286

AAV-h-KLK15-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KLK15 (kallikrein related peptidase 15). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACO; HSRNASPH

Description (Vector)

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID

55554

Gene Name (Vector)

kallikrein related peptidase 15

Gene Symbol

KLK15

HGNC ID

HGNC:20453

ORF Size (aa)

768

ORF Size (bp)

768 bp

RefSeq ID

NM_017509

RefSeq Synonyms

NM_138564, NM_138563, NM_017509, NM_001277082, NM_001277081, BC144046, BC126137, BC069518, BC069507, BC069480,

Species

human

UniGene ID

Hs.567535

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.