human KLK13 shRNA silencing AAV

Name
AAV-h-KLK13-shRNA

Cat No
shAAV-213280

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KLK13.

shAAV-213280

AAV-h-KLK13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KLK13 (kallikrein related peptidase 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

KLK-L4; KLKL4

Description (Vector)

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined.

Gene ID

26085

Gene Name (Vector)

kallikrein related peptidase 13

Gene Symbol

KLK13

HGNC ID

HGNC:6361

ORF Size (aa)

834

ORF Size (bp)

834 bp

RefSeq ID

NM_015596

RefSeq Synonyms

NM_015596, BC069543, BC069334,

Species

human

UniGene ID

Hs.165296

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.