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human KLHL13 shRNA silencing AAV

Name 
AAV-h-KLHL13-shRNA
Cat No 
shAAV-213230
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KLHL13.

shAAV-213230
AAV-h-KLHL13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KLHL13 (kelch like family member 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BKLHD2
Description (Vector)
KLHL13 encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants.
Gene ID
90293
Gene Name (Vector)
kelch like family member 13
Gene Symbol
KLHL13
HGNC ID
HGNC:22931
ORF Size (aa)
1968
ORF Size (bp)
1968 bp
RefSeq ID
NM_033495
RefSeq Synonyms
NM_033495, NM_001168303, NM_001168302, NM_001168301, NM_001168300, NM_001168299, BC064576,
Species
human
UniGene ID
Hs.348262

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.