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human RABL6 shRNA silencing AAV

Name 
AAV-h-RABL6-shRNA
Cat No 
shAAV-213059
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RABL6.

shAAV-213059
AAV-h-RABL6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RABL6 (RAB, member RAS oncogene family-like 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C9orf86; GTP-binding protein Parf; PARF; partner of ARF; pp8875; putative GTP-binding protein Parf; Rab-like GTP-binding protein 1C; Rab-like protein 1; rab-like protein 6; RBEL1
Description (eCommerce)
Rab-like protein 1 (RBEL1) is a member of the Ras superfamily of small GTPases. RBEL1 binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis [taken from NCBI Entrez Gene (Gene ID: 55684)].
Description (Vector)
RABL6 encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
55684
Gene Name (eCommerce)
RAB, member RAS oncogene family like 6
Gene Name (Vector)
RAB, member RAS oncogene family-like 6
Gene Symbol
RABL6
HGNC ID
HGNC:24703
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2061
ORF Size (bp)
2061 bp
Protein Name (eCommerce)
Rab-like protein 6
RefSeq ID
NM_024718
RefSeq Synonyms
NM_024718, NM_001173989, NM_001173988, BC021095, BC002945,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Rab-like protein 1 (RBEL1) is a member of the Ras superfamily of small GTPases. RBEL1 binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis [taken from NCBI Entrez Gene (Gene ID: 55684)].
UniGene ID
Hs.370555
UniProt ID (eCommerce)
Q3YEC7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.