human KIAA1530 shRNA silencing AAV

Name
AAV-h-KIAA1530-shRNA

Cat No
shAAV-213019

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human UVSSA.

shAAV-213019

AAV-h-KIAA1530-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UVSSA (UV stimulated scaffold protein A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

KIAA1530; UVSS3

Description (Vector)

UVSSA appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex to help repair UV-induced DNA damage. Defects in this gene can cause UV-sensitive syndrome 3.

Gene ID

57654

Gene Name (Vector)

UV stimulated scaffold protein A

Gene Symbol

UVSSA

HGNC ID

HGNC:29304

ORF Size (aa)

2130

ORF Size (bp)

2130 bp

RefSeq ID

NM_020894

RefSeq Synonyms

NM_020894, NM_001317935, NM_001317934, BC140901, BC110331, BC021930,

Species

human

UniGene ID

Hs.380475

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.