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human KIAA0226 shRNA silencing AAV

Name 
AAV-h-KIAA0226-shRNA
Cat No 
shAAV-212895
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RUBCN.

shAAV-212895
AAV-h-KIAA0226-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RUBCN (RUN and cysteine rich domain containing beclin 1 interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
76
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
baron; beclin-1 associated RUN domain containing protein; KIAA0226; RUBICON; RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein; run domain Beclin-1-interacting and cysteine-rich domain-containing protein; rundataxin; SCAR15
Description (eCommerce)
Rubicon (RUN domain and cysteine-rich domain containing Beclin 1- interacting protein) was identified as a protein that associates with Beclin 1 and found to regulate endocytic trafficking and autophagy at the maturations step.
Gene ID
9711
Gene Name (eCommerce)
RUN and cysteine rich domain containing beclin 1 interacting protein
Gene Name (Vector)
RUN and cysteine rich domain containing beclin 1 interacting protein
Gene Symbol
RUBCN
HGNC ID
HGNC:28991
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2919
ORF Size (bp)
2919 bp
Protein Name (eCommerce)
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein
RefSeq ID
NM_014687
RefSeq Synonyms
NM_014687, NM_001346873, NM_001145642, BC160011,
Research Areas
Autophagy,Cell Biology,Golgi Apparatus,Lysosome
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Rubicon (RUN domain and cysteine-rich domain containing Beclin 1- interacting protein) was identified as a protein that associates with Beclin 1 and found to regulate endocytic trafficking and autophagy at the maturations step.
UniGene ID
Hs.478868
UniProt ID (eCommerce)
Q92622

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.