human KCNV2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KCNV2.
shAAV-212794
AAV-h-KCNV2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KCNV2 (potassium voltage-gated channel modifier subfamily V member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
KV11.1; Kv8.2; RCD3B
Description (Vector)
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.
Gene ID
169522
Gene Name (Vector)
potassium voltage-gated channel modifier subfamily V member 2
Gene Symbol
KCNV2
HGNC ID
HGNC:19698
ORF Size (aa)
1638
ORF Size (bp)
1638 bp
RefSeq ID
NM_133497
RefSeq Synonyms
NM_133497, BC101353, BC101352,
Species
human
UniGene ID
Hs.660831
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.