human KCNQ5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KCNQ5.
shAAV-212774
AAV-h-KCNQ5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KCNQ5 (potassium voltage-gated channel subfamily Q member 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Kv7.5
Description (Vector)
KCNQ5 is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
56479
Gene Name (Vector)
potassium voltage-gated channel subfamily Q member 5
Gene Symbol
KCNQ5
HGNC ID
HGNC:6299
ORF Size (aa)
2772
ORF Size (bp)
2772 bp
RefSeq ID
NM_019842
RefSeq Synonyms
NM_019842, NM_001160134, NM_001160133, NM_001160132, NM_001160130, BC143554, BC117359,
Species
human
UniGene ID
Hs.675919
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.