human KCNK10 shRNA silencing AAV

Name 
AAV-h-KCNK10-shRNA
Cat No 
shAAV-212732
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KCNK10.

shAAV-212732
AAV-h-KCNK10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNK10 (potassium two pore domain channel subfamily K member 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
K2p10.1; PPP1R97; TREK-2; TREK2
Description (Vector)
KCNK10 belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene ID
54207
Gene Name (Vector)
potassium two pore domain channel subfamily K member 10
Gene Symbol
KCNK10
HGNC ID
HGNC:6273
ORF Size (aa)
1632
ORF Size (bp)
1632 bp
RefSeq ID
NM_021161
RefSeq Synonyms
NM_138318, NM_138317, NM_021161, BC075022, BC075021,
Species
human
UniGene ID
Hs.560255

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.