human KCNJ8 shRNA silencing AAV

Cat. No: shAAV-212729

Availability: 4-5 weeks

Name: AAV-h-KCNJ8-shRNA

This is an AAV expressing shRNA for silencing of Human KCNJ8.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNJ8
Gene Name: potassium voltage-gated channel subfamily J member 8
Gene ID: 3764
Gene Synonyms: KIR6.1; uKATP-1
ORF Size: 1275 bp
RefSeq#: NM_004982
Gene Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS).
UniGene ID: Hs.619408
HGNC ID: HGNC:6269