human KCNH5 shRNA silencing AAV

Name
AAV-h-KCNH5-shRNA

Cat No
shAAV-212700

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KCNH5.

shAAV-212700

AAV-h-KCNH5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNH5 (potassium voltage-gated channel, subfamily H (eag-related), member 5). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EAG2; H-EAG2; Kv10.2;

Description (Vector)

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. This gene is not expressed in differentiating myoblasts. Alternative splicing results in three transcript variants encoding distinct isoforms.

Gene ID

27133

Gene Name (Vector)

potassium voltage-gated channel, subfamily H (eag-related), member 5

Gene Symbol

KCNH5

HGNC ID

HGNC:6254

ORF Size (aa)

2967

ORF Size (bp)

2967 bp

RefSeq ID

NM_139318

RefSeq Synonyms

NM_172376, NM_172375, NM_139318, BC073979,

Species

human

UniGene ID

Hs.27043

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.